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The Company
VIRxSYS is a leading company in the field of RNA biology
and therapeutics. As the only RNA trans-splicing company, VIRxSYS utilizes
its patented, broad-based technology known as spliceosome mediated RNA
trans-splicing or SMaRT™ to re-write the genetic message at the
level of pre-messenger RNA. Gene reprogramming is achieved through trans-splicing,
a naturally occurring process, and mediated by VIRxSYS's patented RNA
molecules known as pre-trans-splicing molecules (PTMs).
The specific application of SMaRT™ depends upon the nature of the
genetic material that is trans-spliced into a pre-mRNA target. Applications
include RNA therapeutics, real time molecular imaging, genomics, determination
of alternate splice sites and molecular evolution, amongst others. VIRxSYS’
initial focus with this technology is on RNA therapeutics.
VIRxSYS has strong first-mover advantages in the RNA therapeutic field
utilizing trans-splicing. Four US patents with broad claims are issued
and 46 applications are pending.
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