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The Company Intronn is best known for developing and patenting spliceosome-mediated RNA trans-splicing (SMaRT™) technology, a new approach to genetic medicine. Unlike most RNA technologies that deploy RNA modifications as “gene-silencers” to block selected gene functions, the SMaRT™ technology reprograms gene expression at the RNA level by inserting a new sequence into a gene to repair mutations or change gene expression. “We see tremendous synergy between our two technologies. SMaRT™ reinforces our successful RNA antisense approach in our VRX496 therapy,” said Dr. Rautsola. “Combining the VIRxSYS delivery platform with the SMaRT™ RNA reprogramming technology will help us create powerful new therapies more rapidly. Our initial focus will continue to be on HIV and genetic diseases. Intronn brings advanced pre-clinical programs in hemophilia and cardiovascular disease, which will integrate extremely well with our own programs in those areas. We also envision applications of SMaRT™ in a broad range of disease indications.” About VIRxSYS |
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